General Knowledge MCQs
Topic Notes: General Knowledge
MCQs and preparation resources for competitive exams, covering important concepts, past papers, and detailed explanations.
Plato
- Biography: Ancient Greek philosopher (427–347 BCE), student of Socrates and teacher of Aristotle, founder of the Academy in Athens.
- Important Ideas:
- Theory of Forms
- Philosopher-King
- Ideal State
3101
Which drug was approved by the FDA in November 2025 for treating relapsed or refractory acute myeloid leukemia (AML) with a susceptible nucleophosmin 1 mutation?
Answer:
Komzifti (ziftomenib)
Komzifti (ziftomenib) received FDA approval in November 2025 for treating adults with relapsed or refractory acute myeloid leukemia who have a specific nucleophosmin 1 (NPM1) mutation.
3102
A November 2025 study revealed that venom from which creature could be used to develop molecules that kill breast cancer cells as effectively as chemotherapy?
Answer:
Amazonian scorpion
Research published in November 2025 showed that molecules derived from the venom of an Amazonian scorpion could kill breast cancer cells with efficacy comparable to chemotherapy, offering a new potential avenue for cancer treatment.
3103
In late 2024, Google released which experimental AI model series designed specifically for the 'agentic era'?
Answer:
Gemini 2.0
Google released the first models in its Gemini 2.0 experimental series in December 2024, positioning them as models designed for the 'agentic era' with enhanced capabilities for taking actions and executing multi-step plans.
3104
What specifically does the drug 'Redemplo' (plozasiran), approved by the FDA in November 2025, target in adults?
Answer:
High triglycerides
Redemplo (plozasiran) was approved by the FDA in November 2025 specifically to reduce triglycerides in adults with familial chylomicronemia syndrome (FCS), a rare genetic disorder.
3105
Researchers from UC Davis engineered which crop in November 2025 to encourage soil bacteria to convert atmospheric nitrogen into fertilizer, potentially reducing the need for synthetic fertilizers?
Answer:
Wheat
In November 2025, UC Davis researchers announced they had engineered wheat to secrete compounds that trigger soil bacteria to fix atmospheric nitrogen, creating a natural fertilizer system that could lower agricultural emissions.
3106
Which major tech company unveiled significant updates to its humanoid robot 'Optimus' in October 2025, highlighting improvements in dexterity and balance?
Answer:
Tesla
Tesla unveiled updates to its Optimus humanoid robot in October 2025, demonstrating enhanced physical capabilities such as better balance, object manipulation, and autonomous navigation for factory and logistics applications.
3107
In November 2025, the FDA approved which drug for the treatment of locally advanced or metastatic non-squamous non-small cell lung cancer with specific HER2 mutations?
Answer:
Hyrnuo (sevabertinib)
On November 19, 2025, the FDA approved Hyrnuo (sevabertinib) for treating adults with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) harboring activating HER2 tyrosine kinase domain mutations.
3108
Which AI model, detailed in Nature Medicine in September 2025, was reported to outperform WHO recommendations in predicting flu vaccine strains?
Answer:
VaxSeer
VaxSeer, a new machine-learning platform detailed in Nature Medicine in September 2025, outperformed WHO recommendations by accurately matching dominant flu strains in retrospective tests, offering a potentially more accurate alternative for vaccine formulation.
3109
What is the primary condition for the 'Sim Blocking' of non-filers?
Answer:
Failure to file Income Tax Returns despite having taxable income
The FBR initiated the blocking of mobile SIM cards for individuals who possess taxable income but have failed to file their Income Tax Returns.
3110
Which province launched the 'Pink Bus Service' specifically for women?
Answer:
Sindh
The Sindh government launched the Pink Bus Service in cities like Karachi and Hyderabad to provide safe and dedicated transport for women.