September 2025 Edition
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September 2025 Current Affairs MCQs & Solutions
Top national & international current affairs questions for CSS, PMS, FPSC, PPSC, and NTS screening tests.
#881
Which drug was approved in August 2025 for treating diffuse midline glioma with a specific H3 K27M mutation?
(a) Modeyso (dordaviprone)
(b) Hernexeos (zongertinib)
(c) Ibtrozi (taletrectinib)
(d) Zegfrovy (sunvozertinib)
Explanation: Modeyso (dordaviprone) was approved in August 2025 for the treatment of diffuse midline glioma, a serious brain tumor, specifically in patients harboring the H3 K27M mutation.
#882
In November 2025, scientists developed a tiny ingestible pill that detects what condition by glowing?
(a) Stomach ulcers
(b) Intestinal bleeding
(c) Colon cancer
(d) Acid reflux
Explanation: A new ingestible pill developed in November 2025 contains engineered bacteria that glow when they encounter heme, a component of blood, thereby acting as a non-invasive detector for intestinal bleeding.
#883
What is the primary function of the drug 'Inluriyo' (imlunestrant), approved in September 2025?
(a) Treating lung cancer
(b) Treating breast cancer
(c) Treating prostate cancer
(d) Treating skin cancer
Explanation: Inluriyo (imlunestrant) was approved in September 2025 for the treatment of estrogen receptor-positive, HER2-negative advanced or metastatic breast cancer.
#884
Researchers in November 2025 found that Vitamin D3 supplementation could halve the risk of what event?
(a) Bone fracture
(b) Second heart attack
(c) Stroke
(d) Developing diabetes
Explanation: A study published in November 2025 indicated that Vitamin D3 supplementation could reduce the risk of suffering a second heart attack by approximately 50%.
#885
Which term describes the 2025 robotics trend of robots made from pliable materials to handle delicate objects?
(a) Elastic Robotics
(b) Soft Robotics
(c) Fluid Robotics
(d) Flex-Bots
Explanation: Soft Robotics is a growing trend in 2025 involving the creation of robots from soft, flexible materials. This allows them to handle delicate items like fruit or electronics without damaging them.
#886
Which drug was approved in June 2025 for treating ROS1-positive non-small cell lung cancer?
(a) Ibtrozi (taletrectinib)
(b) Andembry (garadacimab)
(c) Lynozyfic (linvoseltamab)
(d) Zegfrovy (sunvozertinib)
Explanation: Ibtrozi (taletrectinib) received FDA approval in June 2025 for the treatment of patients with locally advanced or metastatic ROS1-positive non-small cell lung cancer.
#887
In November 2025, a new airflow device was introduced that can capture indoor germs almost immediately. Which university's engineers developed it?
(a) MIT
(b) UBC Okanagan
(c) Stanford
(d) Oxford
Explanation: Engineers at the University of British Columbia (UBC) Okanagan developed a new airflow device in November 2025 that traps exhaled aerosols and pathogens almost immediately to prevent disease spread indoors.
#888
Which drug was approved in July 2025 to treat relapsed or refractory multiple myeloma?
(a) Lynozyfic (linvoseltamab)
(b) Ekterly (sebetralstat)
(c) Zegfrovy (sunvozertinib)
(d) Anzupgo (delgocitinib)
Explanation: Lynozyfic (linvoseltamab) was approved in July 2025 for treating adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy.
#889
A November 2025 study on leukemia immunotherapy utilized which cell death mechanism to boost anti-tumor defenses?
(a) Apoptosis
(b) Necroptosis
(c) Autophagy
(d) Ferroptosis
Explanation: The study found that inducing necroptosis, a form of programmed inflammatory cell death, in cancer cells could dramatically boost the body's immune attack against leukemia.
#890
Which company released the 'Llama' series of open-source language models, with significant updates in 2024 and 2025?
(a) Google
(b) Meta
(c) Microsoft
(d) Amazon
Explanation: Meta Platforms released the Llama series of models (including Llama 3 in 2024), which became a standard for open-source large language models in the AI community.
#891
Which drug, approved in August 2025, targets HER2 tyrosine kinase domain mutations in non-small cell lung cancer?
(a) Hernexeos (zongertinib)
(b) Wayrilz (rilzabrutinib)
(c) Dawnzera (donidalorsen)
(d) Brinsupri (brensocatib)
Explanation: Hernexeos (zongertinib) was approved in August 2025 for adults with unresectable or metastatic non-squamous non-small cell lung cancer specifically harboring HER2 tyrosine kinase domain activating mutations.
#892
In February 2025, Intuitive Machines' IM-2 mission launched with the Nova-C lander named 'Athena'. What was the specific landing site targeted by this mission?
(a) Malapert A
(b) Mons Mouton
(c) Schrödinger Basin
(d) Shackleton Crater
Explanation: The IM-2 mission targeted Mons Mouton, a flat-topped mountain near the lunar south pole, specifically chosen to hunt for water ice using the PRIME-1 drill.
#893
Which major milestone did SpaceX's Starship achieve for the first time during its fifth flight test in late 2024/early 2025?
(a) Reaching the Moon
(b) Successful catch of the Super Heavy booster by the launch tower arms
(c) Deploying 100 Starlink satellites
(d) Docking with the ISS
Explanation: During the fifth flight test, SpaceX successfully caught the Super Heavy booster using the 'Mechazilla' launch tower arms, a historic feat for reusable rocket technology.
#894
The NASA ESCAPADE mission, designed to study Mars' magnetosphere, was launched in November 2025 aboard which debut rocket?
(a) Vulcan Centaur
(b) Falcon Heavy
(c) New Glenn
(d) Ariane 6
Explanation: The ESCAPADE mission was launched aboard the maiden flight of Blue Origin's 'New Glenn' rocket in November 2025.
#895
What was the outcome of the Intuitive Machines IM-2 'Athena' landing in March 2025?
(a) Perfect upright landing
(b) Landed sideways/tipped over
(c) Crashed on impact
(d) Failed to reach lunar orbit
Explanation: The Athena lander touched down but ended up on its side (similar to IM-1), which limited its solar power generation and led to an early end of the mission.
#896
The European Space Agency's 'Euclid' telescope released its 'Quick Data Release 1' (Q1) in March 2025. Approximately how many new strong gravitational lenses did it identify?
(a) 50
(b) 100
(c) 500
(d) 1000
Explanation: The Q1 data release from Euclid revealed approximately 500 new strong gravitational lens candidates, significantly increasing the known number of such objects.
#897
Which Chinese spacecraft was launched in November 2025 explicitly to assist or retrieve astronauts stranded on the Tiangong space station?
(a) Shenzhou 20
(b) Shenzhou 21
(c) Shenzhou 22
(d) Tianzhou 8
Explanation: China launched Shenzhou 22 in November 2025 to assist the crew, following issues with a previous spacecraft that delayed the return of astronauts.
#898
In January 2025, Firefly Aerospace launched its first 'Blue Ghost' lunar lander. What is the name of this specific mission?
(a) Ghost Riders in the Sky
(b) Dark Side of the Moon
(c) Lunar Pathfinder
(d) Artemis Scout
Explanation: Firefly Aerospace named its first Blue Ghost mission 'Ghost Riders in the Sky'. It launched in January 2025 to deliver NASA CLPS payloads.
#899
The Starlab commercial space station project passed which critical NASA milestone in March 2025?
(a) Critical Design Review (CDR)
(b) Preliminary Design Review (PDR)
(c) Launch Readiness Review (LRR)
(d) Final Assembly
Explanation: Starlab Space LLC successfully completed the Preliminary Design Review (PDR) with NASA in March 2025, signaling its design was technically sound to proceed to full development.
#900
Which NASA mission performed a gravity assist flyby of Mars in March 2025 on its way to Jupiter?
(a) Juno
(b) Lucy
(c) Europa Clipper
(d) Psyche
Explanation: NASA's Europa Clipper, launched in October 2024, executed a Mars gravity assist flyby in March 2025 to gain the necessary speed to reach Jupiter.