A sequel (تسلسل) is a book, film, or event that follows or is a 'continuation' (جاری) of an earlier one. 'Sound with a sharp note' (تیز آواز) is 'squeal'.

Sententious (پندآمیز) means 'pompous and moralizing' (پرتکلف اور اخلاقیات کا درس دینے والا); given to making pompous, moralizing speeches.

A sensor (حساس آلہ) is a device that detects changes in the environment. A 'smoke detector' (دھوئیں کا پتہ لگانے والا) is a common example of a sensor. 'One who criticizes' (تنقید کرنے والا) is a 'censor'.

To seize (قبضہ کرنا) means to take hold of suddenly and forcibly, or to 'confiscate' (ضبط کرنا) something by authority. 'Discard' (پھینک دینا) means to throw away.

A segment (حصہ) is a 'portion' (ٹکڑا) or part into which something is divided. 'Piece of pottery' (مٹی کا ٹکڑا) is 'potsherd'.

To seethe (غصے سے کھولنا) means (of a liquid) to boil, or (of a person) 'to be extremely upset' (شدید غصے میں ہونا) or angry, often inwardly.

Sedentary (بیٹھے رہنے والا) means (of a person) tending to spend much time seated, or (of work) characterized by much sitting. 'Inactive' (غیر فعال) is the best synonym.

Sedate (پرسکون) means 'calm' (پُرامن), dignified, and unhurried. As a verb, it means to give someone a calming drug.

Secular (غیر مذہبی) means 'having nothing to do with religion' (جس کا مذہب سے کوئی تعلق نہ ہو); not spiritual or sacred.

Scrupulous (باضمیر) means diligent, thorough, and extremely attentive to details. 'Conscientious' (فرض شناس) is a direct synonym. 'Reckless' (لاپرواہ) is an antonym.